论文部分内容阅读
目的了解哈尔滨市体检人群高尿酸血症(HUA)的患病情况及其危险因素。方法采用分层整群随机抽样方法对哈尔滨市3 551例参加健康体检的人群进行体格和生化检查。运用SPSS 20.0软件进行t检验和χ2检验,运用Logistic回归分析HUA的相关危险因素,P<0.05为差异有统计学意义。结果所调查的人群中,男性血尿酸水平为(362.64±80.47)μmol/L,女性为(271.49±66.55)μmol/L,男性高于女性(t=36.89,P<0.05);男性HUA患病率为24.27%,女性为9.62%,男性高于女性(χ2=133.36,P<0.05),男性中,HUA患病率以19~29、30~39岁年龄组最高,分别为29.73%、29.74%;多因素logistic回归分析表明,男性、肥胖、血脂代谢异常和脂肪肝是HUA患病的主要危险因素(OR>1,P<0.05)。结论本调查研究体检人群男性HUA的患病率较高,且发病呈年轻化趋势;HUA与肥胖、血脂代谢异常及脂肪肝的关系密切。
Objective To understand the prevalence and risk factors of hyperuricemia (HUA) in medical examination population in Harbin. Methods The stratified cluster random sampling method was used to examine the physical and biochemical status of 3 551 healthy people in Harbin. Using SPSS 20.0 software t test and χ2 test, the use of Logistic regression analysis of the risk factors associated with HUA, P <0.05 for the difference was statistically significant. Results In the surveyed population, the serum uric acid level was (362.64 ± 80.47) μmol / L in males and 271.49 ± 66.55 μmol / L in males, and was higher in males than in females (t = 36.89, P <0.05) The prevalence of HUA was the highest in men aged 19-29 and 30-39 years, respectively, 29.73% and 29.74%, respectively, with a rate of 24.27% and 9.62% in females (χ2 = 133.36, P <0.05) %. Multivariate logistic regression analysis showed that males, obesity, dyslipidemia and fatty liver were the main risk factors for HUA (OR> 1, P <0.05). Conclusion The prevalence of HUA in the male was higher than that of male in the survey, and the incidence of HUA was younger. The prevalence of HUA was closely related to obesity, dyslipidemia and fatty liver.