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本文对国产的奥拉西坦进行了４２３例痴呆的临床试验。研究方法为随机双盲阳性药物（脑复康）对照及开放试验。疗效评价方法采用ＭＭＳＥ量表。Ｂｌｅｓｓｅｄ行为量表，自觉症状评分和操作试验等。试验组采用口服奥拉西坦２．４ｇ／ｄ，６０ｄ为一疗程。共３２７例（包括双盲试验组与开放组），显效５２例（２３．３％）有效１３０例（５８．３％），总有效率（显效率＋有效率）为８１．０％。试验组与对照组比较无显著性差异，Ｐ＞０．０５。不良反应极轻微。以上结果表明奥拉西坦与脑复康疗效相似。
This article conducted a clinical trial of 423 cases of dementia on domestic oxiracetam. The study was randomized double blind positive drug (Naofukang) control and open trial. Efficacy evaluation method using MMSE scale. Blessed behavior scale, subjective symptom score and operation test. The experimental group used oral oxiracetam 2.4g / d, 60d for a course of treatment. A total of 327 cases (including double-blind trial group and open group), effective in 52 cases (23.3%) effective 130 cases (58.3%), the total effective rate (significant efficiency + effective rate) was 81.0%. The experimental group and the control group showed no significant difference, P> 0.05. Adverse reactions are minimal. The above results show that oxiracetam and brain rehabilitation similar effect.