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目的:比较液基薄层细胞学(TCT)与相应宫颈活检病人的符合率,探讨如何提高宫颈癌前病变诊断的准确率。方法:对TCT检查异常并进行阴道镜检查的352例患者进行回顾性对比分析。结果:TCT检查结果为:ASC-US+AGC-US 177例,ASC-H34例,LSIL112例,HSIL29例。宫颈活检结果为:慢性炎症165例,CINⅠ97例,CINⅡ38,CINⅢ28例,癌24例。两者的符合率分别为:ASC-US+AGE-US 33.3%,ASC-H88.2%,LSIL 63.49%,HSIL 93.1%。宫颈癌及高级别上皮内瘤变的高发年龄为30~39岁,且有年轻化趋势。结论:TCT与宫颈活检的符合率高,尤其对宫颈高级别上皮内瘤变和宫颈癌的发现率高,但也存在一定的假阳性和假阴性,因此对TCT检查异常者应及时进行活检或随访,防止漏诊或过度治疗。
Objective: To compare the coincidence rate between TCT and corresponding cervical biopsy and to explore how to improve the diagnostic accuracy of cervical precancerous lesions. Methods: A retrospective comparative analysis of 352 patients with abnormal TCT and colposcopy was performed. Results: The results of TCT were 177 cases of ASC-US + AGC-US, 34 cases of ASC-H, 112 cases of LSIL and 29 cases of HSIL. Cervical biopsy results: 165 cases of chronic inflammation, CIN Ⅰ 97 cases, CIN Ⅱ 38, CIN Ⅲ 28 cases, 24 cases of cancer. The coincidence rates of the two were as follows: ASC-US + AGE-US 33.3%, ASC-H88.2%, LSIL 63.49% and HSIL 93.1% respectively. Cervical cancer and high-grade intraepithelial neoplasia of the high incidence of age 30 to 39 years, and a younger trend. Conclusion: The coincidence rate of TCT and cervical biopsy is high, especially for the detection of high-grade cervical intraepithelial neoplasia and cervical cancer, but there are also some false positives and false negatives. Therefore, TCT abnormalities should be promptly biopsy or Follow-up to prevent missed diagnosis or over-treatment.