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目的研究分析左乙拉西坦单药治疗不同类型小儿癫痫的临床效果。方法 102例不同类型的小儿癫痫患儿,均给予左乙拉西坦单药治疗,观察患儿临床治疗总有效率和不良反应情况。结果部分型癫痫患儿治疗总有效率为88.24%,强直型为77.78%,强直阵挛型为80.95%,眼肌阵挛型为100.00%,肌阵挛型为87.50%,继发全面性为78.57%,总有效率为83.33%。所有患儿均未出现严重并发症,其中行为异常1例,易怒、烦躁7例,睡眠障碍2例,体重增加3例,嗜睡4例,学习能力降低1例,并发症发生率为17.65%(18/102)。结论左乙拉西坦单药治疗不同类型小儿癫痫具有显著的临床效果,能够有效提高临床疗效,安全可靠,值得临床推广。
Objective To study the clinical effect of levetiracetam monotherapy on different types of pediatric epilepsy. Methods A total of 102 children with epilepsy of pediatric epilepsy were treated with levetiracetam monotherapy, and the total effective rate and adverse reactions in clinical treatment were observed. Results The total effective rate was 88.24%, 77.78% for tonic type, 80.95% for tonic type, 100.00% for opsoclonus type and 87.50% for myoclonus type. The secondary comprehensiveness was 78.57%, the total effective rate was 83.33%. All patients had no serious complications, including 1 case of abnormal behavior, 7 cases of irritability and irritability, 2 cases of sleep disturbance, 3 cases of weight gain, 4 cases of drowsiness, 1 case of decreased learning ability, and the complication rate was 17.65% (18/102). Conclusion Levetiracetam monotherapy for the treatment of different types of pediatric epilepsy has a significant clinical effect, which can effectively improve the clinical efficacy, safety and reliability, it is worth clinical promotion.