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目的探讨阿托伐他汀治疗冠心病合并高血脂患者的临床疗效。方法 80例冠心病合并高血脂患者,随机分为对照组和实验组,各40例。对照组采用常规药物治疗,实验组在常规药物治疗的基础上联合使用阿托伐他汀药物治疗,比较两组患者的临床治疗效果和不良反应情况。结果使用阿托伐他汀药物治疗后,对照组的临床治疗总有效率为80.0%,实验组的临床治疗总有效率为97.5%。实验组的临床治疗效果明显优于对照组(P<0.05)。对照组的不良反应发生率为20.0%,实验组为5.0%,实验组的不良反应发生率显著低于对照组,差异具有统计学意义(P<0.05)。结论阿托伐他汀治疗冠心病合并高血脂患者具有良好的治疗效果,且治疗安全性高,值得在临床上推广使用。
Objective To investigate the clinical efficacy of atorvastatin in patients with coronary heart disease complicated with hyperlipidemia. Methods 80 cases of coronary heart disease with hyperlipidemia were randomly divided into control group and experimental group, 40 cases in each. The control group was treated with conventional drugs. The experimental group was treated with atorvastatin on the basis of conventional drug therapy. The clinical effects and adverse reactions of the two groups were compared. Results After treatment with atorvastatin, the total effective rate of clinical treatment in the control group was 80.0%. The total effective rate of clinical treatment in the experimental group was 97.5%. The clinical efficacy of the experimental group was significantly better than that of the control group (P <0.05). The incidence of adverse reactions in the control group was 20.0% and that in the experimental group was 5.0%. The incidence of adverse reactions in the experimental group was significantly lower than that in the control group (P <0.05). Conclusions Atorvastatin has a good therapeutic effect in patients with coronary heart disease complicated with hyperlipidemia and is safe in treatment. It is worth to be popularized in clinic.