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胰腺实性-假乳头状肿瘤(solid-pseudopapillary tumor of pancreas,SPTP)是一种少见的胰腺肿瘤,占胰腺肿瘤的0.17%~2.70%,1959年由Frantz首先报道,曾被误认为神经内分泌肿瘤或囊性肿瘤,2000年WHO将SPTP归类为交界性或有一定恶性潜能的肿瘤。对于肿瘤起源,一直有争议,多数学者认为,SPTP可能起源于生殖脊或卵巢始基相关细胞。本研究通过对5例SPTP的临床病理及免疫组化特征分析,提高对SPTP的诊断、鉴别诊断及生物学行为的认识。
Pancreatic solid pseudopapillary tumor of pancreas (SPTP) is a rare pancreatic tumor, accounting for 0.17% ~ 2.70% of pancreatic tumors, first reported by Frantz in 1959, had been mistaken for neuroendocrine tumors Or cystic tumor, 2000 WHO classification of SPTP as borderline or have certain malignant potential of the tumor. The origin of the tumor has been controversial, most scholars believe that SPTP may originate in the reproductive ridges or ovarian primordial related cells. In this study, we analyzed the clinicopathological and immunohistochemical features of 5 cases of SPTP to improve the diagnosis, differential diagnosis and biological behavior of SPTP.