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４０ 只雄性Ｗｉｓｔａｒ大鼠分为正常对照组和制模组，大鼠慢性血清病肾炎模型形成后，将制模组大鼠按体重随机分为模型组、虫草肾康组（虫草组）、强的松组。虫草组和强的松组灌胃相应药物，最后同时测定各组血生化指标、尿蛋白、循环免疫复合物（ＣＩＣ）、红细胞Ｃ３ｂ受体阳性花环率、红细胞免疫复合物阳性花环率、Ｔ细胞总数和肾脏病理改变。结果表明，尿蛋白虫草组轻于模型组，血清白蛋白高于模型组（Ｐ＜０．０５），红细胞免疫复合物阳性花环率、ＣＩＣ低于模型组，红细胞Ｃ３ｂ受体阳性花环率高于模型组（Ｐ＜ ０．０５），肾小球病理改变轻于模型组，提示虫草肾康可改善红细胞免疫粘附功能，降低ＣＩＣ，减轻肾小球病理损伤，减少尿蛋白
Forty male Wistar rats were divided into normal control group and model group. After the formation of rat model of chronic serum nephritis, the model rats were randomly divided into model group, Cordyceps sinensis group (Cordyceps group), and weight. The pine group. Cordyceps group and prednisone group were intragastrically administered with corresponding drugs. Finally, blood biochemical indicators, urinary protein, circulating immune complex (CIC), red blood cell C3b receptor positive rosette rate, red blood cell immune complex positive rosette rate, and T cell were measured at the same time. Total and renal pathological changes. The results showed that the urinary protein Cordyceps was lighter than the model group, serum albumin was higher than the model group (P<0.05), the rate of positive rosettes and CIC of red blood cell immune complexes was lower than that of the model group, and the rate of red blood cell C3b receptor positive rosette was higher than that of the model group. In the model group (P<0.05), the glomerular pathological changes were lighter than those in the model group, suggesting that Chongcao Shenkang can improve red blood cell immune adhesion function, reduce CIC, reduce glomerular pathological damage, and reduce urinary protein