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目的:探讨介入治疗输卵管妊娠的新方法。材料与方法:采用Seldinger技术,对12例输卵管妊娠患者进行超选择性子宫动脉插管经导管灌注氨甲蝶呤(MTX)后,明胶海绵颗粒栓塞子宫动脉,术后定期监测血B-HCG水平变化及盆腔情况。结果:输卵管妊娠在血管造影下呈I、Ⅱ、Ⅲ型3种表现。I型表现者2例,Ⅱ型表现者3例及Ⅲ型表现者中2例,达治愈标准。血B-HCG在术后12天内降至正常,月经在32~42天内恢复正常。月经干净3天行HSG,其中5例输卵管显示通畅,2例输卵管远端不全梗阻。治愈7例中1例术后半年宫内妊娠。开腹手术者5例血管造影均呈Ⅲ型表现。其中2例病理切片证实胚胎组织已坏死。结论:赵选择性子宫动脉插管化疗药物灌注及血管栓塞治疗输卵管妊娠,能保留生殖器官,保存生育能力,不失为又一种保守治疗输卵管妊娠的方法。对血管造影下,不同表现类型与治疗效果上的差异需进一步深入研究。
Objective: To explore a new method of interventional treatment of tubal pregnancy. Materials and Methods: Seldinger technique was used to screen the uterine arteries of gelatin sponge particles after transperitoneal uterine arterial catheterization of methotrexate (MTX) in 12 patients with tubal pregnancy. Blood B-HCG levels were monitored regularly Changes and pelvic conditions. Results: Tubal pregnancy in angiography showed I, Ⅱ, Ⅲ type three kinds of performance. 2 cases of type I performance, 3 cases of type II performance and 2 cases of type III performance, up to standard cure. Blood B-HCG decreased to normal within 12 days after operation and menstruation returned to normal within 32-42 days. Menstrual clean 3 days HSG, 5 cases of tubal showed patency, 2 cases of distal tubal obstruction. One case of intracranial pregnancy was cured in 7 cases in 6 months after operation. 5 cases of open surgery angiography showed type Ⅲ performance. Two of the pathological sections confirmed that the embryonic tissue was necrotic. Conclusion: Zhao selective uterine artery infusion of chemotherapy drugs and vascular embolization tubal pregnancy, reproductive organs can retain, save fertility, after another conservative treatment of tubal pregnancy method. For angiography, the difference between the different types of performance and treatment effect needs further study.