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目的：研究末期妊娠孕母及初生婴儿血清叶酸、VB12含量的相关情况。方法：叶酸、VB12放射免疫测定法。结果：末期妊娠妇女叶酸缺乏发生率高（48．39％）。初生婴儿叶酸缺乏也普通。孕母VB12正常与否其相应初生婴儿脐血VB12含量差异有显著性，孕母正常组初生婴儿脐血VB12明显高于孕母降低组。结论：常规测定本期孕妇血清叶酸JB12含量，对明显低于正常者，应予以适当补充治疗。
Objective: To study the correlation between serum folic acid and VB12 in pregnant women and newborns in the end of pregnancy. Methods: Folic acid, VB12 radioimmunoassay. Results: The incidence of folic acid deficiency in late pregnancy was high (48.39%). Newborn baby folic acid deficiency is also common. The difference of VB12 content in umbilical cord blood of the corresponding newborns was significant when the pregnant women VB12 was normal or not. The level of VB12 in the umbilical blood of the newborn infants of the normal pregnant women was significantly higher than that of the pregnant women. Conclusion: The routine determination of serum folic acid JB12 levels in pregnant women in this period was significantly lower than normal, should be appropriate treatment.