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本实验测定了36只大鼠经胃肠道给予吗氯贝胺30mg/kg后不同时刻的血药浓度,血药浓度经3P87药物动力学程序包计算其在大鼠体内的Tp为0.36h,消除半衰期T_(1/2)为1.64h。该药在大鼠体内呈开放单房室模型配置。
In this study, 36 rats were measured by the gastrointestinal tract after dovibramine 30mg / kg at different times after the plasma concentration, plasma concentration calculated by the 3P87 pharmacokinetic package in rats Tp was 0.36h , Elimination half-life T_ (1/2) is 1.64h. The drug is an open single-chamber model in rats.