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[目的]探讨急性单核细胞性白血病病人的乳酸脱氢酶。[方法]选取2004年1月～2011年1月我院收治的70例初诊急性单核细胞性白血病患者及40例健康体检者,观察健康体检者、急性单核细胞性白血病患者治疗前后的乳酸脱氢酶水平。[结果]与对照组比较,治疗前组及复发组患者乳酸脱氢酶水平明显升高(P﹤0.01);与治疗前组比较,完全缓解组患者乳酸脱氢酶水平明显降低(P﹤0.01)。[结论]动态监测乳酸脱氢酶水平有助于了解急性单核细胞性白血病病人的病情变化,并在一定程度上了解其预后。
[Objective] To investigate the lactate dehydrogenase in patients with acute monocytic leukemia. [Methods] From January 2004 to January 2011 in our hospital admitted 70 cases of newly diagnosed acute monocytic leukemia patients and 40 healthy subjects were observed in healthy subjects, patients with acute monocytic leukemia before and after treatment of lactic acid Dehydrogenase levels. [Results] Compared with the control group, the level of lactate dehydrogenase in pretreatment group and relapse group was significantly increased (P <0.01). Compared with the pretreatment group, the level of lactate dehydrogenase was significantly decreased in the complete remission group (P <0.01) ). [Conclusion] The dynamic monitoring of lactate dehydrogenase level can help to understand the changes of patients with acute monocytic leukemia and to some extent, understand the prognosis.