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雄激素的生理作用贯穿于男性从胚胎发育到衰老的整个生命历程,对男性生活质量有重大影响。随年龄的增长,50岁后的男性当内源性睾酮水平减低时,会出现焦虑、惊恐不安、失眠和情感淡漠等一系列精神心理性疾病的表现。睾酮补充治疗对认知、运动等功能有直接改善作用,可改善老年男性的焦虑、惊恐不安、失眠、记忆力减退以及思维反应和智力减退等。研究迟发性性腺功能减退症(late-onsethypogonadism,LOH)与精神心理疾病的关系十分必要,对预防及治疗老年精神心理疾病有重要临床意义。
The physiological role of androgens throughout the entire life span of male development from embryo to aging has a significant impact on male quality of life. As they age, men with 50 years of age experience reduced levels of endogenous testosterone, causing anxiety, anxiety, insomnia, and apathy. Testosterone replacement therapy has direct effects on cognition, exercise and other functions and can improve anxiety, anxiety, anxiety, insomnia, memory loss, and mental reactions and mental retardation in elderly men. To study the relationship between late-onsexypogonadism (LOH) and mental illness is very important and has important clinical significance in the prevention and treatment of mental illness in the elderly.