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胰岛素抵抗和胰岛β细胞功能缺陷是2型糖尿病发病的两个关键因素,而肝脏是调节体内糖代谢的重要器官,各种肝脏疾病均可使肝脏生理功能受损,通过一系列相关机制引起机体糖代谢紊乱,甚至出现糖耐量减低或糖尿病。在我国,肝损害引起的糖尿病主要以慢性肝炎、肝硬化为主,而在发达国家,非酒精性脂肪肝、酒精性肝硬化、慢性丙型肝炎病毒感染等较为常见。Narmyn于1906年首次提出了肝源性糖尿病(Hepatogenous diabetes,HD)这一概念,把继发于慢性肝功能损害的糖尿病统称为肝源性糖尿病。本文就糖尿病发病与肝脏的关系及其临床处理做一综述。1肝脏在糖尿病发病中的作用我国乙型肝炎和肝硬化
Insulin resistance and pancreatic β-cell function defects are two key factors in the pathogenesis of type 2 diabetes. The liver is an important organ that regulates glucose metabolism in vivo. All kinds of liver diseases can impair the physiological function of the liver and cause a series of related mechanisms Sugar metabolism disorders, or even impaired glucose tolerance or diabetes. In China, the main cause of liver damage caused by chronic hepatitis, liver cirrhosis, while in developed countries, non-alcoholic fatty liver, alcoholic cirrhosis, chronic hepatitis C virus infection are more common. Narmyn first proposed the concept of Hepatogenous Diabetes (HD) in 1906 to collectively refer to diabetes secondary to chronic liver damage as liver-derived diabetes. This article reviews the relationship between diabetes and liver and its clinical treatment. A role of liver in the pathogenesis of diabetes in China Hepatitis B and cirrhosis