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目的：比较内镜套扎术（ＥＶＬ）和硬化疗法（ＥＩＳ）治疗食管静脉曲张破裂出血的疗效和安全性。方法：８４例肝硬化伴食管静脉曲张破裂出血患者随机分为２组，ＥＶＬ组４０例，ＥＩＳ组４４例。ＥＶＬ组患者应用Ｓｔｉｅｇｍａｎｎ－Ｇｏｆｆ结扎设备，每次结扎间隔２周；ＥＩＳ组患者在同样时间间隔内静脉内注射乙氧硬化醇。结果：ＥＶＬ组患者曲张静脉消除率为７５．００（３０／４０，ＥＩＳ组为６３．６０（２／４４）（Ｐ＞０．０５）；ＥＶＬ组患者曲张静脉消除期限为１１．５周±６．０周，ＥＩＳ组为 １８．０周±１４．０周（Ｐ＝０．０３６）； ＥＶＬ组患者出血复发率为３０％（１２／４０），ＥＩＳ组为５０％（２２／４４）（Ｐ＝０．０３）；ＥＶＬ组５例和ＥＩＳ组１３例患者发生各种并发症（Ｐ＜０．００５）；ＥＶＬ组患者食管静脉曲张复发率为５２．５％（２１／４０），ＥＩＳ组为２７．３％（１２／４４）（Ｐ＜０．０５）；ＥＶＬ组２例患者发生门静脉高压性胃病；ＥＶＬ组７例和ＥＩＳ组９例患者死亡，ＥＶＬ组５例和ＥＩＳ组１０例患者治疗失败。结论：ＥＶＬ组患者食管静脉曲张消除较ＥＩＳ组快，并发症发生率低，出血复发率较低但静脉曲张复发率较高，治疗后易发生门静脉高?
Objective: To compare the efficacy and safety of endoscopic ligation (EVL) and sclerosis (EIS) in the treatment of esophageal variceal bleeding. Methods: Eighty-four patients with cirrhosis and esophageal variceal bleeding were randomly divided into two groups: 40 in EVL group and 44 in EIS group. Patients in the EVL group received a Stiegmann-Goff ligation device at 2-week intervals, and patients in the EIS group received intravenous injection of ethoxylated alcohol at the same intervals. Results: The rate of varicocele in EVL group was 75.00 (30/40), that in EIS group was 63.60 (2/44) (P> 0.05), and the duration of varicose veins in EVL group was 11.5 weeks ± 6.0 weeks, 18.0 weeks ± 14.0 weeks in the EIS group (P = 0.036), 30% (12/40) in the EVL group and 50% (22/44) in the EIS group (P = 0.03). There were various complications in 5 patients in EVL group and 13 patients in EIS group (P <0.005). The recurrence rate of esophageal varices in EVL group was 52.5% (21/40) EIS group was 27.3% (12/44) (P <0.05); 2 patients with EVL group had portal hypertensive gastropathy; 7 patients died in EVL group and 9 patients died in EIS group, 5 patients in EVL group and EIS group The treatment failed in 10 patients.Conclusion: The esophageal varices disappeared in EVL patients as compared with those in EIS patients, the incidence of complications was low, and bleeding But a higher incidence of varicose veins lower relapse rate after treatment, prone to high portal?