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背景与目的念珠菌属是普遍存在于哺乳动物和人类皮肤黏膜的微生物。由于念珠菌病复发率很高,唑类真菌药的应用尤为广泛,伴随而来的是高度耐药性。抗微生物光动力治疗(Antimicrobial photodynamic,a PDT)是基于光敏剂联合可见光的一种新兴的抗感染方法。本研究的目的是观察PDT对唑类耐药的白念珠菌菌株的杀真菌效应。材料和方法选取对唑类药物耐药和敏感的白念珠菌菌株为
Background and Objective Candida are microorganisms that are prevalent in mammalian and human mucocutaneous mucosa. Because of the high rate of recurrent candidiasis, the use of azole fungals is particularly widespread, with the attendant high resistance. Antimicrobial photodynamic (a PDT) is a new anti-infective method based on photosensitizer combined with visible light. The aim of this study was to investigate the fungicidal effect of PDT on azole-resistant C. albicans strains. Materials and Methods Candida albicans strains resistant to and susceptible to azole were selected