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卡马西平是一种毒性较低的抗癫痫药物,常见的毒性作用有胃肠道反应、中枢抑制、皮疹和溶血等。本文介绍1例由苯妥英钠、卡马西平所致的肌无力综合征。患者女性,28岁。癫痫史已10余年。常服苯妥英钠、鲁米那、安定等。每月发作1次。1983年12月因扁桃体化脓,咽痛并发讲话不清,舌头上举无力。经用抗生素治疗半月后,扁桃体化脓痊愈,但舌头上举仍无力,晨轻夜重,经用新斯的明后有好转。
Carbamazepine is a less toxic anti-epileptic drugs, common toxic effects of gastrointestinal reactions, central suppression, rash and hemolysis. This article describes a case of phenytoin sodium, carbamazepine-induced myasthenia syndrome. Patient female, 28 years old. Epilepsy history has more than 10 years. Often served phenytoin sodium, luminal, stability and so on. Attack once a month. December 1983 due to tonsil suppurative, sore throat concurrent speech is not clear, the tongue on the move weakness. After treatment with antibiotics for half a month, the tonsil healed, but the tongue is still unable to lift the morning light night weight, after neostigmine improved.