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目的比较伴有心房颤动和窦性心律的慢性心力衰竭(CHF)患者白细胞介素-6(IL-6)、C反应蛋白(CRP)和血管紧张素Ⅱ(AngⅡ)水平变化,探讨其与CHF患者心房颤动中的关系。方法选择已经治疗病情稳定的CHF患者67例(其中伴有心房颤动患者32例和窦性节律患者35例),检测其IL-6、CRP和AngⅡ水平,通过超声心动图测定CHF患者的左室射血分数。结果伴有心房颤动患者的IL-6、CRP和AngⅡ水平较窦性心律患者有显著差异。结论炎症和肾素-血管紧张素-醛固酮系统与CHF患者的心房颤动有关联。
Objective To compare the changes of interleukin-6, C-reactive protein (CRP) and angiotensin Ⅱ (AngⅡ) in patients with chronic heart failure (CHF) accompanied by atrial fibrillation and sinus rhythm, Atrial Fibrillation in Patients. Methods Sixty-seven patients with stable CHF (including 32 patients with atrial fibrillation and 35 patients with sinus rhythm) were enrolled in this study. The levels of IL-6, CRP and AngⅡ were measured by echocardiography. Left ventricular Ejection fraction. Results The levels of IL-6, CRP and AngⅡ in patients with atrial fibrillation were significantly different from those in patients with sinus rhythm. Conclusion The inflammation and renin-angiotensin-aldosterone system are associated with atrial fibrillation in CHF patients.