论文部分内容阅读
目的探讨妊娠期急性脂肪肝(AFLP)的临床特点,为早期诊断、及时合理治疗提供依据,以降低母婴死亡率。方法对陕西中医学院附属医院1998年至今收治的9例AFLP患者的临床资料进行回顾性分析。结果 9例早期均有不同程度的消化道症状。4例合并妊娠期高血压病。1例胎死宫内。实验室检查:9例均有不同程度的肝功损害,7例肾功能损害。6例凝血功能障碍。孕产妇死亡2例,死胎1例。新生儿死亡2例。结论妊娠期脂肪肝是发生在妊娠晚期的一种严重并发症,起病急骤、病情凶险,早期诊断、及时终止妊娠及加强多科协作综合治疗是改善母儿预后的关键。
Objective To investigate the clinical features of acute fatty liver during pregnancy (AFLP) and provide the basis for early diagnosis and timely and reasonable treatment to reduce the maternal and infant mortality rate. Methods The clinical data of 9 AFLP patients admitted to the Affiliated Hospital of Shaanxi College of Traditional Chinese Medicine since 1998 were retrospectively analyzed. Results Nine cases had different degrees of gastrointestinal symptoms in the early stage. 4 cases of pregnancy-induced hypertension. 1 case of fetal death. Laboratory tests: 9 cases had varying degrees of liver damage, 7 cases of renal damage. 6 cases of coagulation disorders. Maternal death in 2 cases, 1 case of stillbirth. Neonatal death in 2 cases. Conclusions Fatty liver during pregnancy is a serious complication occurring in the third trimester of pregnancy. The rapid onset, the dangerous condition, early diagnosis, timely termination of pregnancy and strengthening of multidisciplinary and comprehensive treatment are the keys to improve the prognosis of pregnant women.