Lewis鼠视网膜脉络膜巨噬细胞、MHC－Ⅱ类抗原阳性细胞的免疫组织化学研究

• 作 者: 杨培增
• 机 构: 中山医科大学中山眼科中心
• 出 处: 中华眼底病杂志
• 发表日期: 1995年04期
• 关键词: Ⅱ类抗原 Lewis 阳性细胞 视网膜脉络膜 巨噬细胞 细胞生长 树突 抗原提呈细胞 抗原提呈作用 组织切片

在视网膜平片、脉络膜－巩膜复合体平片及眼组织切片上进行了免疫组织化学研究，在平片上发现，视网膜和脉络膜内均有网状分介的巨噬细胞，脉络膜内尚有网状分布的ＭＨＣ－Ⅱ类抗原阳性细胞，细胞的形态、密度容易辨认和计算。切片则未能显示组织中细胞的分布、确切的形态特征及密度。说明在组织平片上进行免疫组化研究具有重要价值。本研究结果并提示：巨噬细胞、ＭＨＣ－Ⅱ类抗原阳性细胞在维持视网膜和脉络膜免疫环境的稳定性和防御感染等方面可能起重要作用．

Immunohistochemistry was performed on retinal slices, choroid-sclera complex plain films and ocular tissue sections. On the plain film, macrophages were found in the retina and choroid, and there were reticular Distribution of MHC-Ⅱ antigen-positive cells, cell morphology, density and easy identification and calculation. Slices failed to show the distribution of cells in the tissue, the exact morphological characteristics and density. It is of great value to study the immunohistochemistry on the plain film. The results of this study also suggest that macrophages and MHC class II antigen-positive cells may play an important role in maintaining the stability of the retina and choroid immune environment and preventing infection.