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从皮肤感染部位取材的染色涂片中,测定麻风杆菌生活力的形态指数(MI)是快速评价麻风病化疗效果的标准之一,尤其在治疗早期是这样。用萋尼(ZN)氏法染色的涂片中菌体均匀一致,且整个菌体深染的麻风菌(完整菌)可认为是有生活力的,反之,不完整着色的麻风菌(非完整菌)则是没有生活力的。作者测定了利福平、B663和B1912对小鼠足垫中麻风杆菌完整菌比率(SR)的影响,并评
Morphology index (MI), a measure of the viability of Leprosy, is one of the criteria for rapid assessment of the efficacy of leprosy chemotherapy, particularly in the early stages of treatment, from stained smears taken from infected skin sites. Bacteria stained evenly by ZN method, and the entire bacterium stained with leprosy (intact bacteria) could be regarded as viable. On the contrary, incompletely colored leprosy (incomplete Bacteria) is not viable. The authors determined the effect of rifampicin, B663 and B1912 on the ratio of leprosy bacilli in mice footpads