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对78例RSV肺炎患儿血清补体的测定结果表明,C_3、C_4、C_5和B因子明显低于对照组,而在56例恢复期患儿中,则显著高于急性期(P<0.001)。同时,以上4种成份在重型组明显低于轻型组。表明补体在急性期有显著的下降,与病情的严重程度一致,并随疾病的恢复而增高。推测以上4种补体可能参与了抗原抗体复合物引起的免疫病理过程。提示通过观察RSV肺炎患儿的血清补体变化,对了解本病的严重程度和发展趋势有一定的参考价值。
The serum levels of C_3, C_4, C_5 and B in 78 children with RSV pneumonia were significantly lower than those in the control group, while those in 56 children with convalescence were significantly higher than those in the acute phase (P <0.001). At the same time, the above four components in the heavy group were significantly lower than the light group. This indicates that there is a significant decrease in complement in the acute phase, consistent with the severity of the disease and increased with the recovery of the disease. It is speculated that these four kinds of complement may be involved in the immunopathological process caused by antigen-antibody complex. Prompt observation of RSV pneumonia in children with serum complement changes, the understanding of the severity of the disease and trends have a certain reference value.