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癫痫是脑机能障碍的一种症状,它可能由各种病因引起。对癫痫的遗传基础已经进行了研究,并且已通过分子遗传学的研究对癫痫基因进行了探索。为了研究癫痫基因,必须要找出癫痫发作的特定的染色体位点。但是癫痫病的染色体定位目前还不知道。弄清染色体异常(染色体位点)与癫痫发作的关系也是很重要的。一些染色体异常如:21三体和18三体,它们伴有癫痫发作的情况已有报道。但是,对于多数染色体异常,由于它们比较罕见,因而知道的还不多。在智力低下和癫痫发作的患者中,染色体异常发生率知道得也不多。我们对患者进行了染色体分析,研究染色体异常效率及癫痫的特征,包括类
Epilepsy is a symptom of brain dysfunction, which can be caused by a variety of causes. The genetic basis of epilepsy has been studied and epileptogenic genes have been explored by molecular genetic studies. In order to study the gene for epilepsy, it is necessary to find out the specific chromosomal location of the seizure. However, the chromosomal location of epilepsy is not yet known. It is also important to understand the relationship between chromosomal abnormalities (chromosomal loci) and seizures. Some chromosomal abnormalities such as: trisomy 21 and trisomy 18, their associated seizures have been reported. However, most chromosomal abnormalities do not know much because they are rarer. In patients with mental retardation and seizures, the incidence of chromosomal abnormalities is not much known. We conducted a chromosomal analysis of patients to study chromosomal abnormalities and the characteristics of epilepsy, including the class