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目的比较大肠癌患者手术和化疗前后血清癌胚抗原变化情况。方法对96例大肠癌患者进行手术和化疗前后血清癌胚抗原测定。结果其中21例患者的血清癌胚抗原在术前高于正常,21例患者经综合治疗后,其中7例下降至正常水平,其他未降。结论测定大肠癌患者手术和化疗前后血清癌胚抗原值对估计大肠癌患者预后及监测疗效和复发具有一定的临床意义。
Objective To compare the changes of serum carcinoembryonic antigen before and after surgery and chemotherapy in patients with colorectal cancer. Methods 96 cases of colorectal cancer patients before and after surgery and chemotherapy serum carcinoembryonic antigen determination. Results The serum carcinoembryonic antigen in 21 patients was higher than normal before operation. After 21 patients were treated by combination therapy, 7 of them decreased to normal level and the others did not decrease. Conclusions The determination of serum CEA value before and after operation and chemotherapy in patients with colorectal cancer has certain clinical significance in estimating the prognosis of patients with colorectal cancer and monitoring the efficacy and recurrence.