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临床上常见因重症感染、严重创伤、休克等导致的严重肺损伤性疾病,患者系因肺部过度炎症反应所致的肺毛细血管膜损伤,严重者可出现肺水肿、肺不张,威胁生命。一旦发生急性呼吸窘迫综合征(ARDS),可多诱发多器官衰竭,临床病死率极高。机械通气是目前临床应用较广泛的治疗严重肺损伤的方法,可有效辅助患者呼吸,提高肺组织氧交换能力,进一步减少肺损伤〔1〕。但临床实践表明,传统的机械通气方法给患者带来的损伤较大,
Clinically common due to severe infection, severe trauma, shock and other serious lung injury caused by lung disease caused by excessive inflammation in patients with pulmonary capillary membrane damage, severe pulmonary edema may occur, atelectasis, life-threatening . In the event of acute respiratory distress syndrome (ARDS), multiple organ failure can be induced, the clinical mortality rate is extremely high. Mechanical ventilation is currently more widely used in clinical treatment of severe lung injury, which can effectively assist patients breathing, improve oxygen exchange capacity of lung tissue and further reduce lung injury 〔1〕. However, clinical practice shows that the traditional mechanical ventilation to patients with greater damage,