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小鼠ｉｇ水解珍珠层粉５０ｍｇ／ｋｇ．ｄ，１００ｍｇ／ｋｇ，ｄ及２００ｍｇ／ｋｇ．ｄ，共１５ｄ，测定谷胱甘肽过氧化物酶（ＧＳＨ－ＰＸ）活性，血清过氧化脂质及组织脂褐素含量的变化。结果显示，各剂量组均可显著提高全血谷胱甘肽过氧化物酶活力（Ｐ＜０．０５或Ｐ＜０．０１）；１００及２００ｍｇ·ｋｇ（－１）组可以显著降低血清过氧化脂质的含量（Ｐ＜０．０１）；１００及２００ｍｇ·ｋｇ（－１）组可以显著降低肝、心脂褐素的含量（Ｐ＜０．０５或Ｐ＜０．０１）。但各剂量组对脑脂褐素含量的降低不显著。
Mouse ig hydrolyzed nacre powder 50mg/kg. d, 100 mg/kg, d and 200 mg/kg. d, A total of 15 days, determination of glutathione peroxidase (GSH-PX) activity, serum lipid peroxidation and tissue lipofuscin content changes. The results showed that the glutathione peroxidase activity of whole blood was significantly increased in each dose group (P<0.05 or P<0.01); the serum levels of 100 and 200 mg·kg(-1) could significantly reduce the serum level. Oxidized lipid content (P <0.01); 100 and 200 mg · kg (-1) group can significantly reduce liver and heart lipofuscin content (P <0.05 or P <0.01). However, the decrease of lipofuscin content was not significant in each dose group.