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目的观察放射治疗缓解骨转移癌疼痛的疗效。方法 50例癌症合并骨转移患者采用6-MV直线加速器实施放射治疗:常规分割组32例,2Gy/次,5次/周,每日放射治疗1次,总量40-60Gy/4-6周;低分割组18例,3-5Gy/次,3次/周,隔日放射治疗1次,总量30-50Gy/2.5-4周。结果完成随访3个月-5年。1年生存率24.0%(12/50),2年生存率16.0%(8/50),3年生存率6.0%(3/50)。常规分割组止痛显效率为87.5%,与低分割组的83.3%相仿(P>0.05)。结论放射治疗对恶性肿瘤骨转移引起的疼痛具有良好的止痛效果,而低分割放疗止痛效果与常规分割相当,但能够缩短治疗时间。
Objective To observe the curative effect of radiotherapy to relieve the pain of bone metastatic carcinoma. Methods Fifty patients with cancer complicated with bone metastasis underwent radiotherapy with 6-MV linear accelerator: 32 patients in conventional group, 2Gy / time, 5 times / week, and once daily radiotherapy for 40-60 Gy / 4-6 weeks ; Low-cut group 18 cases, 3-5Gy / time, 3 times / week, radiation treatment every other day, the total 30-50Gy / 2.5-4 weeks. Results were followed up for 3 months to 5 years. The 1-year survival rate was 24.0% (12/50), 2-year survival rate was 16.0% (8/50), and 3-year survival rate was 6.0% (3/50). The effective rate of pain relief in the conventional group was 87.5%, which was similar to 83.3% in the low group (P> 0.05). Conclusion Radiation therapy has a good analgesic effect on the pain caused by bone metastases of malignant tumors, while the analgesic effect of low-radiotherapy is equivalent to that of conventional radiotherapy, but it can shorten the treatment time.