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目的探讨和分析结节病的18F-FDG PET/CT表现,为结节病的正确诊断提供依据。方法回顾性分析16例的结节病患者的临床资料及PET/CT表现,分析总结病变累及部位、大小、标准摄取值(SUV)特点。结果有咳嗽、胸闷等症状者12例,无症状者4例;淋巴结累及者16例:15例累及纵隔及双肺门淋巴结,5例累及锁骨上窝淋巴结,4例累及腹腔或腹膜后淋巴结,2例累及腹股沟淋巴结;有临床症状者淋巴结大小为(27.42±8.92)mm,无临床症状者(26.25±8.54)mm,两者无统计学差异(P<0.918)。两组代谢均有不同程度的增加,有临床症状者SUV最大值(8.34±3.54),无临床症状者SUV最大值(4.20±2.56),两者无统计学差异(P<0.273)。结外脏器累及:双肺多发结节影或斑片影8例,胸膜累及2例,皮肤累及1例,所有结外病灶代谢均有增加,SUV最大值为1.5～4.5不等。结论 PET/CT能准确地反映结节病的病灶分布范围和病灶活性,为临床诊断和治疗提供依据。
Objective To investigate and analyze the 18F-FDG PET / CT findings of sarcoidosis and provide evidence for the correct diagnosis of sarcoidosis. Methods The clinical data and PET / CT findings of 16 patients with sarcoidosis were retrospectively analyzed. The characteristics of affected site, size and standard uptake (SUV) were analyzed. The results of cough, chest tightness and other symptoms in 12 cases, 4 cases of asymptomatic; lymph node involvement in 16 cases: 15 cases involving mediastinal and hilar lymph nodes, 5 cases involving the supraclavicular fossa lymph nodes, 4 cases involving the peritoneal or retroperitoneal lymph nodes, 2 cases involved inguinal lymph nodes; those with clinical symptoms had lymph node size of (27.42 ± 8.92) mm and no clinical symptoms (26.25 ± 8.54) mm, with no significant difference (P <0.918). There was no difference between the two groups (P <0.273). The maximum SUV of clinical symptoms was 8.34 ± 3.54 and the maximum SUV of no clinical symptoms was 4.20 ± 2.56. The extranodal involvement involved multiple nodules or patches in the lungs, 8 cases of pleural involvement, 1 case of skin involvement, and an increase of all extranodal lesions. The maximum SUV ranged from 1.5 to 4.5. Conclusion PET / CT can accurately reflect the distribution of lesions and lesions of sarcoidosis, and provide the basis for clinical diagnosis and treatment.