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结直肠癌带来了巨大疾病负担，已成为全球重大公共卫生问题。通过对全球结直肠癌发病、死亡、生存数据的回顾，总结其在年龄、性别、地区和部位上的分布差异及其发展趋势，提示不同国家地区处在结直肠癌防治的不同阶段，应推动发达国家在结直肠癌防控上成功经验在全球不断普及，积极制定和实施与自身资源相匹配的结直肠癌预防和控制策略，以应对结直肠癌不断上升的挑战。“,”The increasing disease burden caused by colorectal cancer has become one of the major public health problems. This paper analyzes the global statistical data of colorectal cancer, including the morbidity, mortality and case survival, to understand the differences in its age, gender, regional and site specific distributions as well as its incidence trend. The results showed that the programs on colorectal cancer prevention and control varied with country and region. It is necessary to promote developed countries to share their experiences in colorectal cancer prevention and control with developing countries and develop and implement targeted colorectal cancer prevention and control strategies to address the more severe challenge of colorectal cancer.