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目的:分析尿激酶对急性脑梗患者血清中TNF-α表达水平的影响。方法:选取48例急性脑梗塞患者随机分为两组,对照组采取常规治疗方法,观察组采取尿激酶溶栓治疗,观察两组患者的临床疗效,探讨尿激酶对急性脑栓塞患者血清中TNF-α表达水平的影响。结果:与对照组相比,观察组患者治疗效果明显,在溶栓后2小时及6小时TNF-α表达水平明显下降,与其临床疗效和预后具有密切相关性。结论:尿激酶能够降低TNF-α,减轻患者的脑细胞损伤,提高患者的临床疗效。
Objective: To analyze the effect of urokinase on TNF-α in serum of patients with acute cerebral infarction. Methods: Forty-eight patients with acute cerebral infarction were randomly divided into two groups. The control group was treated by conventional therapy. The observation group was treated with urokinase thrombolysis. The clinical curative effect was observed in both groups. The urinary kinase in serum of patients with acute cerebral embolism -α expression levels. Results: Compared with the control group, the therapeutic effect of the observation group was obvious. The expression of TNF-α decreased significantly at 2 hours and 6 hours after thrombolysis, which was closely related to its clinical efficacy and prognosis. Conclusion: Urokinase can reduce TNF-α, reduce brain cell injury in patients and improve the clinical efficacy.