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目的观察依沙吖啶羊膜腔内注射配伍口服米非司酮用于引产的疗效及安全性。方法将58例中期妊娠要求引产的妇女分为两组,各29例,观察组口服米非司酮50mg/12h,共200mg,第3天上午采用羊膜腔内注射依沙吖啶100mg。对照组单用羊膜腔内注射依沙吖啶100mg。结果用药至宫缩开始时间、用药至胎儿及附属物排出的时间(平均娩出时间)、产时产后出血量等并发症2组间差异有显著性(P<0.05),2组均无软产道裂伤。结论米非司酮与利凡诺联合用于中孕引产安全有效。
Objective To observe the efficacy and safety of ethacridine in combination with oral administration of mifepristone for induction of labor. Methods Fifty-eight women with induced labor during the second trimester of pregnancy were divided into two groups (n = 29 in each group). The observation group was given mifepristone 50mg / 12h orally for 200mg. On the third day, amniotic fluid was injected into the amniotic cavity 100mg. Control group alone with amniotic fluid injection of ethacridine 100mg. Results There was no significant difference in complications between the two groups (P <0.05), the time from medication to contractions, the time from administration to fetus and appendages (mean time to delivery), postpartum postpartum hemorrhage and other complications Laceration Conclusion The combination of mifepristone and rivanol is safe and effective for induction of labor during pregnancy.