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既往有关痤疮患者雄激素是否增高的报道是互相矛盾的。本文对病程一年以上,常规治疗无效,导致畸型瘢痕的囊肿性痤疮患者,系统地研究和评价了患者的内分泌功能,并进行治疗试验。女性59例,平均年龄24.7±3.5岁,(合并肥胖1例,多毛症21例、继发性闭经4例、月经紊乱15例)。男性32例,平均年龄21.5岁。用放射免疫测定血中睾酮,5—α一双氢睾酮、雄甾烯二酮、硫酸去氢表雄酮(DHEA-S)、17-羟孕酮、皮质醇、11-脱氧皮质醇,性激
Previous reports of whether androgen levels are elevated in patients with acne are contradictory. This article for more than one year duration, routine treatment ineffective, leading to cicatricial scar of patients with cystic acne, the systematic study and evaluation of the patient’s endocrine function, and treatment trials. There were 59 females with an average age of 24.7 ± 3.5 years old (1 with obesity, 21 with hirsutism, 4 with secondary amenorrhea and 15 with menstrual disorders). 32 males, average age 21.5 years old. Serum testosterone, 5-alpha-dihydrotestosterone, androstenedione, DHEA-S, 17-hydroxyprogesterone, cortisol, 11-deoxycortisol,