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目的探讨尿蛋白排出量与2型糖尿病患者糖尿病足病的相关性,为临床治疗和预防糖尿病足部溃疡提供依据。方法选择2007年1月至2010年6月在内分泌科住院的344例糖尿病足病患者,按wagnar分级法分为6级,测定24h尿蛋白定量,分析糖尿病足病分级与尿蛋白定量的关系。结果糖尿病足病患者wagnar分级与24h尿蛋白值呈正相关。结论 2型糖尿病患者糖尿病足病分级与尿蛋白定量呈正相关,早期进行24h尿蛋白定量测定,对预防和治疗2型糖尿病患者足部溃疡有重要意义。
Objective To investigate the correlation between urinary protein excretion and diabetic foot disease in type 2 diabetic patients and provide evidence for clinical treatment and prevention of diabetic foot ulcer. Methods 344 patients with diabetic foot disease hospitalized in Department of Endocrinology from January 2007 to June 2010 were divided into 6 grades by wagnar grading method. The proteinuria of 24 hours urinary protein was measured. The relationship between diabetic foot disease classification and urinary protein quantitation was analyzed. Results There was a positive correlation between wagnar grade and 24-hour urinary protein in patients with diabetic foot. Conclusions There is a positive correlation between diabetic foot disease and urinary protein in patients with type 2 diabetes. Early determination of urinary protein in 24 hours is of great significance in the prevention and treatment of foot ulcers in type 2 diabetic patients.