噻嗪类利尿剂诱发酷似蛛网膜下腔出血的低钠血症

• 作 者: 王林
• 出 处: 实用医学杂志
• 发表日期: 1987年05期
• 关键词: 噻嗪类利尿剂 蛛网膜下腔出血 双氢克尿塞 充血性心力衰竭 精神错乱 稀释性低钠血症 血清钠 低钠血症 毫渗量 临床状况

本文报告1例噻嗪类利尿剂诱发的严重稀释性低钠血症,其临床表现酷似蛛网膜下腔出血。患者女性,83岁。因轻度充血性心力衰竭服用“Moduretic”1片(氨氯吡脒5毫克,双氢克尿塞50毫克),每日1次。次晨查血清钠130毫摩/升。4天后患者精神错乱,病情急剧恶化,出现头痛、呕

This article reports a case of thiazide diuretic-induced severe dilutional hyponatremia, its clinical manifestations resemble subarachnoid hemorrhage. Patient female, 83 years old. Take 1 tablet of “Moduretic” (Aramdidine 5 mg, Hydrochlorothiazide 50 mg) once daily for mild congestive heart failure. The next morning to check serum sodium 130 mmol / liter. After 4 days, the patient was mentally disturbed and his condition deteriorated sharply. He had a headache and vomiting