论文部分内容阅读
继1975年Kohler和Milstcin报告用杂交瘤技术生产单克隆抗体之后,1979年Kung等用此技术制出针对人T淋巴细胞表面抗原的单克隆抗体,以后陆续生产出一系列针对不同T细胞亚群表面抗原的单克隆抗体,使对T细胞亚群的深入研究成为可能,因之对以T细胞为核心的免疫调节机理的研究也有了长足的进展。一、免疫调节与免疫调节障碍T细胞具有辨认特异性抗原、执行效应细胞的机能,以及调节细胞和
Following the 1975 Kohler and Milstcin report of hybridoma technology to produce monoclonal antibodies, Kung et al. (1979) used this technique to generate monoclonal antibodies against human T lymphocyte surface antigens and subsequently produced a series of monoclonal antibodies directed against different T cell subsets Monoclonal antibodies against surface antigens make it possible to further study T cell subsets. Therefore, great progress has been made in the study of the immune regulation mechanism of T cells. First, immunomodulatory and immunomodulatory disorders T cells have the ability to identify specific antigens, perform effector cells, and regulate cells and