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蒽环类是当今世界上研究最广泛深入的一类抗癌抗生素,阿霉素是其中重要的一个。经过广泛的动物和临床研究证明阿霉素抗瘤谱广、作用强,在多种人类肿瘤中有较好的抗瘤疗效。例如,阿霉素对恶性淋巴瘤(包括何杰金氏病及非何杰金氏病)、乳癌、急性白血病,卵巢癌、软组织肉瘤、胃癌、小细胞性肺癌和膀胱癌等均有较好的疗效。阿霉素对食道癌、鼻咽癌、睾丸癌、甲状腺癌、肝癌、头颈部肿瘤、多发性骨髓瘤和小儿实体瘤也有一定疗效。但是,阿霉素的毒副反
Anthracycline is one of the most widely studied anti-cancer antibiotics in the world. Adriamycin is an important one of them. After a wide range of animal and clinical studies have shown that doxorubicin broad anti-tumor spectrum, strong role in a variety of human tumors have good anti-tumor efficacy. For example, doxorubicin has a good effect on malignant lymphomas (including Hodgkin’s disease and non-Hodgkin’s disease), breast cancer, acute leukemia, ovarian cancer, soft tissue sarcoma, gastric cancer, small cell lung cancer and bladder cancer Efficacy. Adriamycin on esophageal cancer, nasopharyngeal cancer, testicular cancer, thyroid cancer, liver cancer, head and neck cancer, multiple myeloma and pediatric solid tumors have a certain effect. However, the side effects of doxorubicin