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定量研究结肠癌微血管形成与肿瘤侵袭转移和预后的关系。选择７６例结肠癌手术切除标本，应用抗ＣＤ３４单克隆抗体免疫组化ＡＢＣ法对肿瘤组织的微血管进行染色，定量分析微血管数与结肠癌侵袭转移及病人预后的关系。结肠癌组织的微血管数随肿瘤的发展（ＴＮＭ分期）而增加，已发生血行转移的癌肿的微血管数高于区域淋巴转移和无淋巴转移者。对其中５８例有随访资料的病人分析表明，微血管数较高的结肠癌病人的５年生存率显著地低于微血管数较低病人。微血管数定量是判断结肠癌侵袭转移和预后的一个指标。
Quantitative study of the relationship between microvessel formation, invasion, metastasis and prognosis of colon cancer. Seventy-six cases of colon cancer were surgically resected. The microvessels of tumor tissue were stained by anti-CD34 monoclonal antibody immunohistochemical ABC method to quantitatively analyze the relationship between the number of microvessels and colon cancer invasion and metastasis. The number of microvessels in colon cancer tissues increased with tumor progression (TNM staging). The number of microvessels in cancers that had undergone hematogenous metastasis was higher than those in regional lymphatic metastases and those without lymphatic metastases. Analysis of 58 patients with follow-up data showed that the 5-year survival rate of colon cancer patients with a higher number of microvessels was significantly lower than that of patients with lower microvascular numbers. The quantification of microvessels is an indicator of colon cancer invasion, metastasis and prognosis.