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本文报道可乐定(Clonidine)对肾脏疾患所致高血压的治疗效果。病人分三组,即肾动脉狭窄组(5例)。肾脏器质性病变组(6例),本组患者血浆肾素正常。原发性高血压组(8例)。各组治疗方案相同。先测基础血压和肾功,可乐定开始剂量0.15毫克,每日二次,如果舒张压仍高于90毫米汞柱,间隔一周后剂量增至0.3毫克,每日四次。同时使用氯噻嗪500毫克/日。共用药四周。治疗期间和疗程结束后复查血压和肾功。
This article reports the efficacy of clonidine in the treatment of hypertension caused by kidney disease. Patients divided into three groups, namely, renal artery stenosis group (5 cases). Kidney organic disease group (6 cases), this group of patients with normal plasma renin. Essential hypertension group (8 cases). The same treatment programs in each group. First determine the basis of blood pressure and renal function, clonidine dose 0.15 mg, twice daily, if the diastolic blood pressure is still higher than 90 mm Hg, the dose increased to 0.3 mg one week after the interval, four times a day. Chlorphenothiazine 500 mg / day was used at the same time. A total of four weeks medication. Blood pressure and kidney function were reviewed during and after treatment.