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目的探讨不同微创介入治疗对肝癌患者的治疗疗效。方法选取我院收治的肝细胞肝癌患者68例,随机分为两组,一组行肝动脉栓塞化疗,另一组行射频消融治疗。观察两组患者的临床治疗效果,比较两种方法对患者免疫功能的影响,记录两组患者的生存率及并发症发生率。结果经过治疗后,TACE组患者治疗总有效率为55.88%远远低于RAF组患者的总有效率79.41%。TACE组和RAF组患者的CD3、CD4、CD8及CD4/CD8值在术后7d明显变化,TACE组CD3、CD4、CD8及CD4/CD8值远低于RAF组患者。TACE组的1年生存率、3年生存率及5年生存率显著低于RAF组,并发症发生率明显高于RAF组。结论不同的微创介入治疗方法对患者的治疗效果存在明显差异。RAF治疗相比于TACE治疗可明显提高患者的临床效果,减少对患者免疫力的损伤,提高患者生存率,减少并发症的发生,值得临床推广和应用。
Objective To investigate the therapeutic effect of different minimally invasive interventional therapy on patients with liver cancer. Methods Sixty-eight patients with hepatocellular carcinoma who were admitted to our hospital were randomly divided into two groups. One group received hepatic arterial chemoembolization and the other group received radiofrequency ablation. The clinical efficacy of the two groups was observed. The effects of the two methods on immune function were compared. The survival rate and complication rate were recorded. Results After treatment, the total effective rate of treatment in TACE group was 55.88%, which was significantly lower than that in RAF group (79.41%). The values of CD3, CD4, CD8 and CD4 / CD8 in TACE group and RAF group were significantly changed at 7 days after operation. The values of CD3, CD4, CD8 and CD4 / CD8 in TACE group were much lower than those in RAF group. The 1-year survival rate, 3-year survival rate and 5-year survival rate of TACE group were significantly lower than those of RAF group, and the incidence of complications was significantly higher than that of RAF group. Conclusion Different minimally invasive interventional treatments have significant differences in the therapeutic effect of the patients. Compared with TACE treatment, RAF treatment can significantly improve the clinical effect, reduce the patient’s immune system damage, improve patient survival rate and reduce the occurrence of complications, worthy of clinical promotion and application.