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关于急性单核细胞白血病(AMoL)的亚型,历来争论热烈,名词混乱,鉴别诊断困难,现对此综述如下。 AMoL分型的历史演变 AMoL是1913年Schilling等首先报告,是以出现很多过氧化酶染色阴性的大单核吞噬细胞和全身网状内皮细胞增生为特征的急性白血病,认为其白血病细胞来源于肝、脾的网状内皮系统。1931年Naegeli认为单核细胞来源于髓系(粒系)细胞,所谓AMoL在末期移行为原始髓细胞性白血病,实为后者的一种暂时性变型,否认其独立性。从此争论不休。1938年Downey提出一种妥协方案,将A
Subtypes of acute monocytic leukemia (AMoL), has been a heated debate, the terms confusion, differential diagnosis difficult, are summarized below. The historical evolution of AMoL typing AMoL was first reported by Schilling et al in 1913. It is characterized by the appearance of many peroxidase-negative macromonuclear phagocytes and systemic reticuloendothelial leukemia characterized by leukemia cells derived from the liver , Spleen reticuloendothelial system. 1931 Naegeli that monocytes derived from myeloid (myeloid) cells, the so-called AMoL in the final migration of primitive myeloid leukemia, in fact, a temporary variant of the latter, denied its independence. From endless debates. In 1938 Downey proposed a compromise that would