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目的了解广州市越秀区居民各年龄段人群新甲型H1N1流感病毒抗体水平,为完善新甲型H1N1流感疫情防控措施提供科学依据。方法采取多阶段分层随机抽样方法抽取研究对象309人,进行血清标本采集和问卷调查,应用红细胞血凝抑制(HI)方法检测新甲型H1N1流感病毒抗体。结果人群新甲型H1N1流感病毒抗体阳性率为20.06%,0～岁组、6～岁组、10～岁组、16～岁组、25～岁组和60岁以上组的新甲型H1N1流感病毒抗体阳性率分别为18.84%、33.33%、46.67%、30.00%、6.67%和5.00%。6～24岁组的新甲型H1N1流感病毒抗体阳性率较高,为35.00%,无症状抗体阳性率达10.43%。抗体阳性率在性别上差异无统计学意义(P>0.05)。结论广州市越秀区居民新甲型H1N1流感病毒感染状况各年龄段不同,青少年抗体阳性率较高,老年人抗体阳性率相对较低。
Objective To understand the antibody levels of the new influenza A (H1N1) virus in residents of all age groups in Yuexiu District of Guangzhou City, and to provide a scientific basis for improving the prevention and control measures of the new influenza A (H1N1). Methods A total of 309 subjects were recruited by stratified random sampling method. Serum samples were collected and questionnaires were collected. HI antibody was detected by hemagglutination inhibition (HI) method. Results The positive rate of the new influenza A (H1N1) virus in the population was 20.06%. The new influenza A (H1N1) virus in 0-, 6-, 10-, 16-, 25- and 60-year-olds The positive rates of virus antibodies were 18.84%, 33.33%, 46.67%, 30.00%, 6.67% and 5.00%, respectively. The positive rate of new influenza A (H1N1) virus in 6-24 age group was 35.00%, and the positive rate of asymptomatic antibody was 10.43%. The positive rate of antibody had no significant difference in gender (P> 0.05). Conclusions The prevalence of new influenza A (H1N1) virus in residents of Yuexiu District of Guangzhou City is different in all age groups. The positive rate of juvenile antibodies is high, while the positive rate of antibody in seniors is relatively low.