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目的:探讨Ⅰ、Ⅱ期乳腺癌保乳综合治疗的疗效及相关技术,为普及早期乳腺癌保乳综合治疗提供参考。方法:回顾性分析我院1993年12月~2004年10月间216例行保乳手术治疗的乳腺癌患者的相关资料,对肿瘤采取局部扩大切除或乳房象限切除,有209例行腋窝淋巴结清扫。术后辅以放疗、化疗或内分泌治疗。结果:无手术并发症。随访3~147个月,死亡2例,其中1例与本病无关;局部复发率1.85%。按照国家“十五”攻关课题“早期乳腺癌规范化保乳综合治疗的临床研究”采用的乳房美容评定标准进行评价,符合优良标准的有199例(92.13%),不满意者17例(7.87%)。结论:早期乳腺癌保乳综合治疗创伤小、疗效确切、形体改变少、能提高生存质量,但须合理的掌握手术适应证及保乳综合治疗的相关技术。
Objective: To investigate the curative effect and related technologies of breast-conserving breast-conserving therapy in stage Ⅰ and Ⅱ breast cancer, and to provide a reference for popularizing breast-conserving breast-letting comprehensive treatment. Methods: A retrospective analysis of our hospital from December 1993 to October 2004 216 cases of breast conserving surgery in patients with breast cancer related information on the tumor to take a partial expansion or breast quadrant resection, 209 cases of axillary lymph node dissection . Postoperative radiotherapy, chemotherapy or endocrine therapy. Results: No surgical complications. Followed up for 3 to 147 months, 2 died, of which 1 had nothing to do with the disease; the local recurrence rate was 1.85%. According to the standard of breast cosmetic evaluation adopted by the national “Tenth Five-Year” research project “Clinical Research of Standardized Treatment of Early Breast Cancer”, 199 cases (92.13%) and 17 cases (7.87% ). Conclusion: Breast conservative treatment of early breast cancer with small trauma, exact effect, less physical changes, can improve the quality of life, but a reasonable grasp of surgical indications and breast-conserving treatment of related technologies.