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国产胰岛素（生化提取法）经眼吸收后能有效地降低正常和四氧嘧啶糖尿病模型家兔血糖。研究结果表明，胰岛素经眼给药后，能有效地降低两者的血糖浓度。用１％ＥＤＴＡ溶液为吸收促进剂，给正常家兔０．５％和１．０％胰岛素５０ｕｌ后，在１５ｍｉｎ即能发挥作用，维持低血糖状态５ｈ以上。给予糖尿病模型家兔１％和２％胰岛素５０ｕｌ后，在３０ｍｉｎ起效，可使血糖降至常范围内，药物疗效维持５ｈ以上。不加１％ＥＤＴＡ溶液的胰岛素作用明显减小。在０．５％～２．０％的剂量范围内吸收不存在饱和现象，而作用效果存在着浓度依赖性。
Domestic insulin (biochemical extraction) after the eye can effectively reduce the normal and alloxan diabetic rabbit blood glucose. The results show that the insulin administration can effectively reduce the blood glucose levels of both. With 1% EDTA solution as absorption enhancer, 0.5% of normal rabbits and 1.0% of insulin 50ul, can play a role in 15min to maintain hypoglycemia for more than 5h. Given 1% and 2% insulin 50ul in diabetic model rabbits, 30min onset, the blood sugar can be reduced to the usual range, the drug efficacy to maintain 5h or more. Insulin action without EDTA solution was significantly reduced. Absorption in the range of 0.5% ~ 2.0% does not exist saturation phenomenon, and the effect is concentration-dependent.