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[目的]探讨不同治疗方法对早期子宫内膜癌预后的影响。[方法]回顾性分析185例的早期子宫内膜癌患者临床资料,并将其分为5组,单纯手术组37例,单纯放疗组28例,术后放疗组50例,术前全量放疗组35例,术前腔内后装组35例,比较各组5年生存率、局部复发率、远处转移率和放疗并发症。[结果]5年生存率单纯放疗组与术前腔内后装组之间有明显差异(P<0.05)。局部复发率单纯放疗组和单纯手术组与另三组间均有明显差异(P<0.05)。远处转移率各组之间无明显差异(P>0.05)。放疗并发症术前腔内后装组与术后放疗组、术前全量放疗组之间有明显差异(P<0.05)。[结论]早期子宫内膜癌患者治疗仍以手术为主的综合治疗为主,术前腔内后装放疗预后优于术前全量放疗。术前、术后放疗均可降低患者的局部复发率,对改善远处转移无益。
[Objective] To explore the influence of different treatment methods on the prognosis of early endometrial carcinoma. [Methods] The clinical data of 185 patients with early endometrial carcinoma were retrospectively analyzed and divided into 5 groups. 37 patients in the simple operation group, 28 patients in the radiotherapy alone group, 50 patients in the postoperative radiotherapy group, 35 cases, 35 cases of preoperative intracavitary afterloading group, compared 5-year survival rate of each group, local recurrence rate, distant metastasis rate and radiotherapy complications. [Results] There was a significant difference (P <0.05) between 5-year survival rate of radiotherapy group and preoperative intracavitary after-loading group. Local recurrence rate of radiotherapy alone and surgery alone group and the other three groups were significantly different (P <0.05). There was no significant difference between groups in distant metastasis rate (P> 0.05). Radiotherapy complications Preoperative intracavitary afterloading group and postoperative radiotherapy group, preoperative radiotherapy group were significantly different (P <0.05). [Conclusion] The treatment of early endometrial cancer patients is still dominated by comprehensive surgery, the prognosis of preoperative intracavitary posterior radiotherapy is superior to preoperative radiotherapy. Preoperative and postoperative radiotherapy can reduce the local recurrence rate of patients, to improve the distant metastasis is not beneficial.