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目的:观察中西医结合综合治疗儿童手足口病的疗效,探讨手足口病的治疗方案.方法:将患儿分A组336例,予利巴韦林治疗;B组325例,予喜炎平、辨证论治中药内服外洗治疗;C组321例,予A组及B组综合治疗.伴口腔溃疡者,A、B组均予西瓜霜喷剂喷涂,C组联合亚叶酸钙喷涂.比较各组退热时间、疱疹消退时间、口腔溃疡愈合时间、平均留观时间及临床疗效.结果A、B组在口腔溃疡愈合时间,平均留观时间及临床疗效,差异无统计学意义(P＞0.05),但在退热时间、皮疹消退时间B组与A组比较,差异有统计学意义(P＜0.05);C组各项指标及临床疗效均优于A、B组,有显著性差异(P＜0.01).结论:中西医结合综合治疗儿童手足口病疗效显著,重症发生率低,是治疗优选方案,值得推广.“,”Objective:To observe the therapeutic effect of integrative medicine for hand-foot-and-mouth disease in children and to explore the treatment on it.Method:The cases were randomly divided into three groups.Group A (n =336) was treated with Ribavirin ; group B (n =325) was treated with Xiyanpine and differentiation of syndromes combined with oral use and washing with herbal medicine; group C (n=321) was treated with the combination method of group A and group B.To the patients accompanied with oral ulcers,they would be treated with Guilin Watermelon Frost in group A and B,while treated with combined Leucovorin in group C.The time on fever,hand foot mouth tetter and mouth herpes subsidizing,in-hospital and the therapeutic effects were compared in different groups.Results:There was no difference on healing period of oral ulcers,in-hospital time and the therapeutic effect (P＞0.05).While compared group A with group B,there were differences in the time of fever and the rash subsiding (P＜0.05) ; all the indexes in group C were better than that in group A and B,and the statistical difference was significant (P＜0.01).Conclusions:The study demonstrates that the combined therapy of traditional Chinese and western medicine is an effective treatment for hand-foot-and-mouth disease in children,the seriousness rate was low.It is the better method to be chosen for hand-foot-and-mouth disease,thereby deserves further popularization.