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线粒体被认为是源自细菌被真核生物所吞噬而产生共生的结果。但线粒体基因组有部分在漫长的岁月中可迁移到细胞核中。作者发现一个细胞核基因YME2，以前认为是作用于rRNA代谢的基因，对控制线粒体DNA的逸出亦是必需的。YME2的突变可使细胞生长不正常。线粒体中DNA的逸出能引起?
Mitochondria are thought to result from the symbiosis of bacteria eaten by eukaryotes. But part of the mitochondrial genome can migrate into the nucleus over a long period of time. The authors found that a nuclear gene called YME2, previously thought to act on the genes responsible for rRNA metabolism, is also necessary to control the escape of mitochondrial DNA. YME2 mutations can make cell growth is not normal. Mitochondrial DNA escape can cause?