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浆细胞性白血病(PCL)是一种累及血液系统的浆细胞恶性增生性疾病,白细胞分类,其比例大于20％或绝对数大于2×10~9/L。PCL 有两型:多发性骨髓瘤(MM)晚期表现型和没有 MM 原发型。PCL 与 MM 治疗后继发的急性非淋巴细胞性白血病(ANLL)不同,继发性 ANLL 染色体异常与治疗有关,而 PCL 常为复杂的非随机性染色体异常。所有报道病例中,1、8、11和14号染色体受累比例大于60％,13号染色体受累约占40％。本文两例 PCL 核型复杂,均涉及1、8、13等染色体。Bastard 等人也报道过
Plasma cell leukemia (PCL) is a plasma cell malignant proliferative disorder involving the blood system that is classified as a leukocyte in more than 20% or absolute numbers greater than 2 × 10 -9 / L. There are two types of PCL: multiple myeloma (MM) late phenotype and no MM primary. PCL and MM secondary treatment of acute non-lymphocytic leukemia (ANLL) is different from the secondary ANLL chromosomal abnormalities and treatment, and PCL often complex non-random chromosomal abnormalities. In all reported cases, chromosomes 1, 8, 11 and 14 were affected by more than 60% and chromosome 13 by 40%. In this paper, two cases of PCL karyotype complex, all involving 1,8,13 and other chromosomes. Bastard et al. Also reported