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近年来,许多实验结果都证实,环境中存在的杀虫剂可能具有致突变性。因此,这些化合物对人类的危害不仅在于它们的急性毒性,而且也在于它们的致突变作用。杀虫剂可能通过对机体的DNA作用产生致突变性,对DNA的作用有的需要、有的不需要经过代谢活化过程。目前,已有许多试验方法(各种有机体的试验,体内的或体外的试验等等)用于检测各种化学物质的致变特性。然而,检测对人体基因组的损伤,以哺乳动
In recent years, many experimental results have confirmed that pesticides present in the environment may be mutagenic. Therefore, the harm of these compounds to human beings lies not only in their acute toxicity, but also in their mutagenic effects. Pesticides may cause mutagenic effects on the DNA of the body, some of the role of DNA needs, and some do not need to undergo metabolic activation process. Currently, there are many test methods (tests of various organisms, in vivo or in vitro tests, etc.) for detecting the mutagenic properties of various chemicals. However, detecting human genome damage to mammals