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目的:对比非ST段抬高急性冠状动脉综合征(ACS)合并糖尿病患者二联与三联抗血小板的疗效。方法:随机将174例患者分为两联组88例,三联组86例,观察入院72 h及30 d内心脏不良事件。结果:三联组入院72 h与30 d内心脏不良事件分别为4例、9例,两联组分别为16例、25例,两组比较具有统计学差异(P=0.005 1,P=0.007 9)。结论:非ST段抬高ACS合并糖尿病患者早期接受三联抗血小板治疗可有效地减少近期心脏不良事件。
OBJECTIVE: To compare the efficacy of two-part and three-part antiplatelet therapy in patients with non-ST elevation acute coronary syndrome (ACS) complicated with diabetes mellitus. Methods: One hundred and seventy-four patients were randomly divided into two groups (88 cases) and triple therapy group (86 cases). Cardiac adverse events were observed at 72 hours and 30 days after admission. Results: The incidence of cardiac adverse events in the triple combined group at 72 h and 30 d after admission was 4 and 9 respectively. There were 16 cases and 25 cases in the two groups, respectively. There were significant differences between the two groups (P = 0.005 1, P = 0.007 9 ). Conclusions: Early triadic antiplatelet therapy in non-ST-segment elevation ACS patients with diabetes mellitus can effectively reduce recent adverse cardiac events.