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目的:观察急性脑梗死患者血脂、载脂蛋白的变化。方法:选择急性脑梗死患者和健康者,测定血脂、载脂蛋白,并进行组间对比研究。结果:急性脑梗死组血清TG、LDL-C、ApoB水平高于对照组,HDL-C、ApoA1、ApoAl/ApoB比值低于对照组,差异均有统计学意义(P均<0.05)。结论:急性脑梗死组血脂、载脂蛋白与对照组不同,故及时发现指标异常并进行干预可减少急性脑梗死的发生。
Objective: To observe the changes of blood lipids and apolipoproteins in patients with acute cerebral infarction. Methods: Patients with acute cerebral infarction and healthy subjects were selected for determination of serum lipids and apolipoproteins, and comparative study between groups was conducted. Results: The levels of serum TG, LDL-C and ApoB in acute cerebral infarction group were higher than those in control group. The ratios of HDL-C, ApoA1 and ApoAl / ApoB were lower in acute cerebral infarction group than those in control group (all P <0.05). Conclusion: The serum levels of lipids and apolipoproteins in acute cerebral infarction group are different from those in control group. Therefore, the timely detection of abnormal indexes and interventions can reduce the incidence of acute cerebral infarction.