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目的探讨原发性脾脏肿瘤的临床病理特点及外科治疗效果。方法回顾性分析1972年2月至2006年3月间中国医学科学院肿瘤医院收治的43例原发性脾脏肿瘤,按照其临床病理特点进行分类,并就治疗经过及生存率进行统计分析。结果 43例患者中经查体发现者48.8%(21例)。42例行手术切除肿瘤,1例行肿瘤活检。良性16例,其中脾血管瘤15例,脾淋巴管瘤1例;恶性肿瘤24例,其中脾淋巴瘤16例,脾血管肉瘤8例,多数淋巴瘤患者长期生存,3年生存率为88.7%,脾血管肉瘤平均生存时间为10.4个月。结论原发性脾脏肿瘤缺乏特异性症状,B 超和 CT为首选检查方法,手术切除为治疗的主要手段。
Objective To investigate the clinicopathological characteristics and surgical treatment of primary spleen tumors. Methods Retrospective analysis of 43 cases of primary splenic tumors admitted to Tumor Hospital of Chinese Academy of Medical Sciences between February 1972 and March 2006 were classified according to their clinicopathological features and the treatment and survival rates were statistically analyzed. Results Among the 43 patients, 48.8% (21 cases) were found by physical examination. 42 patients underwent surgical resection of the tumor and 1 patient underwent tumor biopsy. 16 cases were benign, including 15 cases of splenic hemangiomas and 1 cases of splenic lymphangioma; 24 cases of malignant tumors including 16 cases of splenic lymphoma and 8 cases of splenic angiosarcoma. The majority of patients with lymphoma had long-term survival and 3-year survival rate of 88.7% The mean survival time of splenic sarcoma was 10.4 months. Conclusion The primary spleen tumors lack of specific symptoms, B-ultrasound and CT as the preferred method of examination, surgical removal of the main means of treatment.